Endocrine Abstracts

Introduction: Tumors derived from the paraganglionic system are rare. 90% of them are located on the adrenal gland, and the remaining 10% are extra-adrenal. Within this last group, 85% are located in the abdomen, 12% in the thorax, and 3% in the head and neck region (HNPG). Its proximity to important structures represents a great difficulty for resection. This makes it necessary to refer these patients to reference centers with multidisciplinary teams and specific surgical tra...

Introduction: GH has been proven to improve lean body mass and muscle strength. We report three cases where growth hormone replacement had a significant effect on gross motor function.Case series: A 15 month old boy was born at 33 weeks of gestation. During infancy, he was noted to have global developmental delay secondary to cerebral atrophy and isolated growth hormone deficiency. He was not able to pull himself to standing position but after commencing...

Introduction: Obesity is nowadays one of the most important challenges in public health and, therefore, the investigation of their causes is most relevant. Among the various behavioral roots of obesity, the emotional over ingestion determined by emotional factors, i.e. emotional eating (EE), is one of them.Objectives: To study how emotions contribute to obesity in woman.Methods: We gathered a convenience sample 220 woman in the hos...

Introduction: Thyroid incidentaloma in 18F-FDG PET-CT is relatively common and the most focal uptake are benign. However, the risk of malignancy of thyroid lesions with focal uptake on 18F-FDG PET-CT is 34.8%. Metastasis to the thyroid is uncommon (less than 0.2% of thyroid fine needle aspiration – FNA - puncture findings), with renal neoplasms being the most frequently associated (48.1%) and, more rarely, those from the breast (7.8%).Case report: A...

Background: Mucormycosis is a serious but rare angio-invasive fungal infection in high-risk patients with diabetes, organ transplantation, neutropenia, and hemochromatosis. The COVID-19 pandemic has been associated with increased incidence of mucormycosis and the incidence has risen more rapidly during the second wave of pandemic in India. The clinical profiles and risk factors for severity and mortality are not very clear among patients with COVID-19 infected with mucormycosi...

Aim: Acromegaly is associated with multiple co-morbidities including diabetes mellitus (DM), obstructive sleep apnoea (OSA), arthropathy, cardiovascular events and malignancies. Early diagnosis and treatment, with an intention to cure or control the growth hormone (GH) exposure can reduce risk of these complications. The aim of this study is to assess the development of acromegaly-related complications amongst patients who have completed at least 10 years of follow up after ac...

Introduction: Adrenal oncocytoma (AO) and ganglioneuroma (GN) are rare causes of adrenal masses, corresponding usually to nonfunctional and benign tumors. However, 20% of the AO shows some elements of malignancy and 10–20% of them affect adrenal hormone production. GNs account for 0.3%-2% of adrenal incidentalomas, with punctate calcifications in CT imaging being highly suggestive. However, preoperative differential diagnosis remains challenging. Adrenal arterial emboliza...

Endocrine Connections, 2018, 7(10): 1031–1039 (DOI: https://doi.org/10.1530/EC-18-0296)...

Primary hyperparathyroidism (PHPT) is a common condition. The prevalence since the introduction of multichannel analysers is approximately 1:1000, with the older female being the typical patient. PHPT is predominantly a sporadic disorder. Surgery remains the only curative approach to most primary hyperparathyroidism (PHPT), medical treatment with cinacalcet has been proven to be an alternative for patients with hyperparathyroidism.Objective: Analyze trea...

Diabetic ketoacidosis (DK) is one of the most serious complications of diabetes mellitus (DM). We performed a case review of DK patients admitted to the intensive care unit (ICU) of our Hospital between 1 June 2012 and 30 June 2016. A demographic analysis was made, time of DM evolution, the therapy and the factors that led to its decompensation. Thus, a total of 42 DK patients were admitted to the ICU in the referred period, mean age was 45 years, a clear predominance of femal...